Transscleral Biopsy of a Choroidal Mass

A 76-year-old woman with a history of breast cancer, basal cell carcinoma, and cutaneous melanoma presented with an 18 mm x14 mm inferonasal lesion 11 mm in height. Given her extensive cancer history, a tissue biopsy was ordered to aid in diagnosis and help determine her treatment plan.

The surgeons created a limited peritomy and looped 2 muscles. A partial-thickness scleral flap provided access to the underlying choroid, and 3 needle passes yielded specimens for pathology and gene-expression profiling.